[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:1] [Pages No:1 - 1]
DOI: 10.5005/jp-journals-10088-11101 | Open Access | How to cite |
Message from the Founder President
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:1] [Pages No:2 - 2]
DOI: 10.5005/jp-journals-10088-11102 | Open Access | How to cite |
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:1] [Pages No:3 - 3]
DOI: 10.5005/jp-journals-10088-11103 | Open Access | How to cite |
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:1] [Pages No:4 - 4]
DOI: 10.5005/jp-journals-10088-11104 | Open Access | How to cite |
Gut–Endocrine Axis - A Route for Diabetes Cure through Surgery?
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:5] [Pages No:7 - 11]
DOI: 10.5005/jp-journals-10088-11105 | Open Access | How to cite |
Abstract
In this review article, we explain the rationale for achieving remission of Diabetes Mellitus by surgical manipulation of the gut endocrine axis, and present the scientific evidence available thus far in support of the same. The evolution of ‘metabolic’ surgery is presented here. The reduction in mortality and co-morbidity is presented. The two main theories of causation of euglycemia are discussed in detail. Most authors now believe in both the theories, and the gastric bypass and the biliary pancreatic diversion are the procedures with the highest rate of remission. Finally, in the context of reappearance of hyperglycemia, the beneficial effects of a prolonged period of normal blood sugar are discussed.
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:2] [Pages No:12 - 13]
DOI: 10.5005/jp-journals-10088-11106 | Open Access | How to cite |
Abstract
Langerhans cell histiocytosis(LCH) is an uncommon neoplasm arising from the histiocytic cells of the dendritic network1. It is commonly seen affecting paediatric population with a systemic involvement (multi-organ involvement), whereas it involves infrequently a single system in the adult population1, 2. The organ systems most frequently affected by LCH in adults are pulmonary system, skeletal system, and cutaneous system. Involvement of endocrine system by LCH in adults is not so common. However, the most common manifestation of endocrine involvement is diabetes insipidus due to the involvement of the posterior pituitary gland1, 2. LCH involvement of the endocrine gland, thyroid is extremely rare3, 4. It is due to the uncommon age group and uncommon organ system of involvement by LCH, we report our case of incidental finding of Langerhans cell Histiocytosis in the thyroid gland in a 29 year old South Indian female.
Management of Insulinoma – Our Institutional (MMC) Experience
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:5] [Pages No:14 - 18]
DOI: 10.5005/jp-journals-10088-11107 | Open Access | How to cite |
Abstract
Introduction Hyperinsulinemia is a clinical syndrome with diverse etiology. Though Insulinoma is rare it is the most common functioning pancreatic islet cell tumour with annual incidence of 0.5-1 per million of the population. Insulinoma is four times more common in females1. They are usually sporadic but may occur as a part of MEN 1 (16%). They occur at any age but present most commonly in middle age. Median age of diagnosis is 47 years for sporadic cases and 23 years for cases associated with MEN I. Most Insulinomas are solitary (90%), small <1cm (65%), intrapancreatic (99%) and or benign (90%). 16% are associated with MEN 1 and are often multiple, malignant in 25% of cases and have high recurrence rate2.
Increased Incidence of Thyroiditis in Recent Years
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:4] [Pages No:19 - 22]
DOI: 10.5005/jp-journals-10088-11108 | Open Access | How to cite |
Abstract
A prospective study was carried out on 123 patients with enlarged thyroid swelling between 16-65 years age group, attending Department of Surgery, Sree Gokulam Medical College and Research Foundation, Venjaramoodu, Trivandrum during the period of November 2011 to February 2013. All patients were examined clinically after taking a detailed history. Then, they were investigated by TFT, USG, X-ray neck, X-ray chest, Indirect Laryngoscopy, FNAC and anti-thyroid antibody tests and all the patients were subjected to surgery and histopathological examination (HPE) of the specimen obtained. Finally, all the reports were analysed and the age distribution, sex distribution and the incidence of thyroiditis in study population was obtained. During the study period 123 cases of enlarged thyroid underwent surgery, out of which 115 were females and 8 male patients. The age of the patient in the study ranged from 16-65 years, the youngest being 16 years old and oldest being 65 years. Maximum cases being in between 30-50 with mean age of 42.3 years. The study showed a female predominance. The incidence of thyroiditis in the present study was 38.21% (47 cases).
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:2] [Pages No:23 - 24]
DOI: 10.5005/jp-journals-10088-11109 | Open Access | How to cite |
Abstract
BACKGROUND Thyroglossal Duct Cysts (TDC) are the most common congenital abnormality seen in the neck. Majority of the cases are benign. However, a rare complication is the development of papillary carcinoma in the cyst. This case report discusses a patient with Papillary Carcinoma of the thyroglossal cyst and papillary carcinoma of the thyroid.
Case of Unusual Cyst in the Neck–Parathyroid Cyst
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:5] [Pages No:25 - 29]
DOI: 10.5005/jp-journals-10088-11110 | Open Access | How to cite |
Abstract
Introduction Parathyroid cysts are rare lesions normally located in the neck and exceptionally in the mediastinum, in about 10% of the cases1. They are normally asymptomatic and frequently omitted in differential diagnosis of neck masses. It is still possible to cause compressive symptomatology, hyperparathyroidism, in addition to recurrent laryngeal nerve paralysis. Cysts may be classified as functioning and nonfunctioning depending on the association with primary hyperparathyroidism; most of the cases are nonfunctioning. Its importance lies in the diagnostic difficulty; it is normally mistaken by thyroid pathology, meaning that it is normally diagnosed only in the surgical act. The purpose of the present study was to report a case of parathyroid cyst that simulated thyroid nodule, discussing diagnostic aspects.
A Case Report of Skeletal Metastases from Papillary Thyroid Carcinoma
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:3] [Pages No:30 - 32]
DOI: 10.5005/jp-journals-10088-11111 | Open Access | How to cite |
[Year:2014] [Month:October] [Volume:11] [Number:1] [Pages:2] [Pages No:33 - 34]
DOI: 10.5005/jp-journals-10088-11112 | Open Access | How to cite |