Indian Journal of Endocrine Surgery and Research

Register      Login

VOLUME 19 , ISSUE 2 ( July-December, 2024 ) > List of Articles

CASE REPORT

Primary Adrenal Leiomyosarcoma: A Rare Case Report

Bharath Shiva, Pooja Ramakant, Prashant K Prusty, Ashwinee Rahalkar, Meghana V Shetty, Asiya Zehra

Keywords : Adrenocortical carcinoma, Case report, Primary adrenal leiomyosarcoma

Citation Information : Shiva B, Ramakant P, Prusty PK, Rahalkar A, Shetty MV, Zehra A. Primary Adrenal Leiomyosarcoma: A Rare Case Report. 2024; 19 (2):73-74.

DOI: 10.5005/jp-journals-10088-11238

License: CC BY-NC 4.0

Published Online: 20-12-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Primary adrenal leiomyosarcoma (PAL) is an extremely rare case finding where the mesenchymal tumor is found to be originating from the mesenchymal elements surrounding the adrenal vessels. Herein we report an interesting case of a 60-year-old gentleman, presenting to us with an abdominal lump. Contrast-enhanced computed tomography of the (CECT) abdomen revealed multilobulated heterogeneously enhancing soft tissue lesion of size 99 × 93 × 33 mm in the left supra renal region. After evaluation, the patient underwent an open left adrenalectomy. Postoperatively the histopathological examination showed mesenchymal neoplasm with spindle-shaped vesicular chromatin, conspicuous nucleoli, and eosinophilic cytoplasm with occasional atypical mitosis.


PDF Share
  1. Zhou Y, Tang Y, Tang J, et al. Primary adrenal leiomyosarcoma: A case report and review of literature. Int J Clin Exp Pathol 2015;8(4): 4258–4263. PMID: 26097622.
  2. Suzuki S, Takahashi N, Sugo M, et al. Challenges in the diagnosis of the enigmatic primary adrenal leiomyosarcoma: Two case reports and review of the literature. BMC Endocr Disord 2023;23:276. DOI: 10.1186/s12902-023-01530-z.
  3. Oshidari B, Zamani A, Bahrami-Motlagh H, et al. Primary leiomyosarcoma of the adrenal; A case report. Int J Surg Case Rep 2022;90:106707. DOI: 10.1016/j.ijscr.2021.106707.
  4. Ramdass MJ, Seelam S, Kumar S. Primary adrenal leiomyosarcoma: A rare entity. Urology Annals 2019;11(4):439–441. DOI: 10.4103/UA.UA_144_18.
  5. Suzuki S, Takahashi N, Sugo M, et al. Challenges in the diagnosis of the enigmatic primary adrenal leiomyosarcoma: Two case reports and review of the literature. BMC Endocr Disord 2023;23:276. DOI: 10.1186/s12902-023-01530-z.
  6. Venyo AKG. Primary leiomyosarcoma of the adrenal gland: A review and update of literature. J Cancer Immunol Ther 2019;2(1): 7–18. DOI: 10.1097/MD.0000000000021061/.
  7. Lacuna K, Bose S, Ingham M, et al. Therapeutic advances in leiomyosarcoma. Front Oncol 2023;13:1149106. DOI: 10.3389/fonc. 2023.1149106.
  8. Deshmukh SD, Babanagare SV, Anand M, et al. Primary adrenal leiomyosarcoma: A case report with immunohistochemical study and review of literature. Cancer Res Ther 2013;9(1):114–116. DOI: 10.4103/0973-1482.110394.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.