Indian Journal of Endocrine Surgery and Research

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VOLUME 18 , ISSUE 2 ( July-December, 2023 ) > List of Articles


The Giants of the Dwarf Family: A Contrasting Tale of Two Giant Parathyroid Adenomas

Somya Arya, Bharath Shiva, Ashutosh Silodia, Vikram Singh Chauhan, Arun Nayak, Sanjay Kumar Yadav

Keywords : Case report, Giant parathyroid, Parathyroid adenoma, Parathyroidectomy, Primary hyperparathyroidism

Citation Information : Arya S, Shiva B, Silodia A, Chauhan VS, Nayak A, Yadav SK. The Giants of the Dwarf Family: A Contrasting Tale of Two Giant Parathyroid Adenomas. 2023; 18 (2):64-66.

DOI: 10.5005/jp-journals-10088-11222

License: CC BY-NC 4.0

Published Online: 12-01-2024

Copyright Statement:  Copyright © 2023; The Author(s).


In the following case report, we are reporting two cases of one of the largest parathyroid adenomas in the literature with two contrasting clinical presentations. The initial case is a 42-year-old female who on initial presentation had severe symptomatic primary hyperparathyroidism (PHPT). Her 4D computed tomography (CT) scan revealed a right inferior parathyroid adenoma (7 × 6 cm) reaching up to the arch of the aorta which was excised trans-cervically. The subsequent patient, a 65-year-old female presented with dyspnea on slight exertion. She did not have any symptoms of PHPT and serum calcium was normal. Computed tomography of her neck revealed multinodular goiter with a right inferior parathyroid adenoma extending up to the arch of the aorta and tracheal compression. Total thyroidectomy with right inferior parathyroidectomy was performed addressing an 8 × 7 cm parathyroid adenoma. The combination of giant parathyroid adenomas which are non-functional is extremely rare, and they should always be considered in the differential diagnosis of neck mass evaluation.

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