Indian Journal of Endocrine Surgery and Research

Register      Login

VOLUME 16 , ISSUE 1 ( Jan-Jun, 2021 ) > List of Articles

CASE REPORT

Collagenous Fibroma Mimicking a Retrosternal Goiter: A Case Report

Priyanka R Singh, Varghese Thomas, Supriya Sen, Shawn S Thomas, Anish J Cherian, Deepak T Abraham, Paul M Jacob

Keywords : Collagenous fibroma, Desmoplastic fibroblastoma, Retrosternal goiter, Soft tissue tumor

Citation Information : Singh PR, Thomas V, Sen S, Thomas SS, Cherian AJ, Abraham DT, Jacob PM. Collagenous Fibroma Mimicking a Retrosternal Goiter: A Case Report. 2021; 16 (1):32-34.

DOI: 10.5005/jp-journals-10088-11152

License: CC BY-NC 4.0

Published Online: 26-08-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Collagenous fibroma, earlier known as desmoplastic fibroblastoma, is a rare fibrous soft tissue tumor that has been described more often in the extremities, where it presents as a slow-growing and painless mass. We report a case of a 48-year-old gentleman, who presented with an anterior neck swelling with substernal extension, resembling a retrosternal goiter, after clinical examination and radiological and cytological assessments. Intraoperatively, we found it to be a mass abutting but separate from the thyroid, arising from the deep aspect of sternum inaccessible from the neck requiring partial-sternotomy for excision. Histopathological examination revealed a hypocellular tumor made of spindle to stellate cells with surrounding stroma showing collagenization with collagen bundles to myxoid changes. This report documents a rare differential for goiter, only the second case reported in the central neck.


PDF Share
  1. Evans HL. Desmoplastic fibroblastoma a report of seven cases. Am J Surg Pathol 1995;19(9):1077–1081. https://journals.lww.com/ajsp/pages/default.aspx
  2. Nielsen GP, O'Connell JX, Dickersin GR, et al. Collagenous fibroma (desmoplastic fibroblastoma): a report of seven cases. Mod Pathol 1996;9(7):781–785. https://www.researchgate.net/journal/Modern-Pathology-1530-0285
  3. Jang JG, Jung HH, Suh KS, et al. Desmoplastic fibroblastoma (collagenous fibroma). Am J Dermatopathol 1999;21(3):256–258. DOI: 10.1097/00000372-199906000-00009.
  4. Osipov V, Carrera G. Collagenous fibroma (desmoplastic fibroblastoma) with vertebral body erosion. Sarcoma 2009;2009:682687. DOI: 10.1155/2009/682687.
  5. Miettinen M, Fetsch JF. Collagenous fibroma (desmoplastic fibroblastoma): a clinicopathologic analysis of 63 cases of a distinctive soft-tissue lesion with stellate-shaped fibroblasts. Hum Pathol 1998;29(7):676–682. DOI: 10.1016/s0046-8177(98)90275-1.
  6. Quinn SF, Erickson SJ, Dee PM. MR imaging in fibromatosis: results in 26 patents with pathologic correlation. Am J Roentgenol 1991;156(3):539–542. DOI: 10.2214/ajr.156.3.1899752.
  7. Hartman TE, Berquist TH, Fetsh JF. MR imaging of extraabdominal desmoids: differentiation from other neoplasms. Am J Roentgenol 1992;158(3):581–585. DOI: 10.2214/ajr.158.3.1738999.
  8. Wilson C, Summerall J, Lubin J, et al. Collagenous fibroma (desmoplastic fibroblastoma): a unique presentation as a goiter in an 88-year-old man. Ann Diagn Pathol 2000;4(3):165–169. DOI: 10.1016/s1092-9134(00)90040-6. PMID: 10919387.
  9. Fong F, Odell E, Simo R. Collagenous fibroma (desmoplastic fibroblastoma) of the neck presenting with neurological symptoms. Head Neck Pathol 2009;3(1):47–50. DOI: 10.1007/s12105-008-0098-6. PMID: 20596989; PMCID: PMC2807529.
  10. World Health Organization Classification of Tumours. Pathology & genetics. Tumours of soft tissue and bone. Lyon, France: International Agency for Research on Cancer; 2002.
  11. Walker KR, Bui-Mansfield LT, Gering SA, et al. Collagenous fibroma (desmoplastic fibroblastoma) of the shoulder. Am J Roentgenol 2004;183(6):1766. DOI: 10.2214/ajr.183.6.01831766.
  12. Shuto R, Kiyosue H, Hori Y, et al. CT and MR imaging of desmoplastic fibroblastoma. Eur Radiol 2002;12(10):2474–2476. DOI: 10.1007/s00330-001-1217-x.
  13. Hasegawa T, Shimoda T, Hirohashi S, et al. Collagenous fibroma (desmoplastic fibroblastoma): report of four cases and review of the literature. Arch Pathol Lab Med 1998;122(5):455–460. https://www.researchgate.net/publication/13691502
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.