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VOLUME 16 , ISSUE 1 ( Jan-Jun, 2021 ) > List of Articles

CASE REPORT

Composite Pheochromocytoma—A Rare Clinical Entity: A Case Series

Pushkar Sharma, Supriya Sen, Paul M Jacob, Santosh Raj, Elanthenral Sigamani, Marie T Manipadam

Keywords : Adrenal, Composite Pheochromocytoma, Ganglioneuroma, Multiple endocrine neoplasia

Citation Information : Sharma P, Sen S, Jacob PM, Raj S, Sigamani E, Manipadam MT. Composite Pheochromocytoma—A Rare Clinical Entity: A Case Series. 2021; 16 (1):28-31.

DOI: 10.5005/jp-journals-10088-11151

License: CC BY-NC 4.0

Published Online: 26-06-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Background: Composite pheochromocytoma is a rare entity with tumor comprising both pheochromocytoma and neuroblastic elements. The clinical outcome of such a composite tumor is not fully understood. In this case series, we report three cases of composite pheochromocytoma managed at our institute from 2016 to 2021. Results: We had three patients with MEN2A syndrome with composite tumor who underwent adrenalectomy, all of which were ganglioneuroma with pheochromocytoma. None of the three cases had recurrence or metastasis associated with composite adrenal tumor on 13-month mean follow-up. Conclusion: We noticed a higher incidence of syndromic association in composite adrenal tumors. The clinical and radiological presentation was dominated by the pheochromocytoma component.

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